Endoluminal laser-Doppler measurements of jejunal perfusion in patients undergoing liver transplantation
| Autor: | Styrbjörn Friman, Lars Mjörnstedt, Lars Bäckman, Kari-Lie Karlsen, Michael Olausson, Anders Aneman, Ebbe Rønholm |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Multiple Organ Failure Dissection (medical) Liver transplantation Catheterization Jejunum Intestinal mucosa Risk Factors Monitoring Intraoperative Laser-Doppler Flowmetry Medicine Humans Transplantation business.industry Hemodynamics Laser Doppler velocimetry Middle Aged medicine.disease Surgery Liver Transplantation medicine.anatomical_structure business Multiple organ dysfunction syndrome Nuclear medicine Perfusion |
| Zdroj: | Transplant International. 14:24-30 |
| ISSN: | 1432-2277 0934-0874 |
| DOI: | 10.1111/j.1432-2277.2001.tb00005.x |
| Popis: | Patients undergoing liver transplantation are at risk of developing the multiple organ dysfunction syndrome, and attention has been focused on the pathogenic role of decreased gastro-intestinal mucosal perfusion. The aim of this study was to investigate the use of laser-Doppler flowmetry for determination of jejunal perfusion. In 10 patients an endoluminal laser-Doppler catheter was positioned with the tip in the jejunum for continuous measurements of jejunal perfusion. The anhepatic phase was associated with a progressive decrease in jejunal perfusion to 49 (40/65)% (P < 0.01) of dissection phase value. At the end of surgery the jejunal perfusion had increased to 134 (103/158)% (P < 0.01) of dissection phase jejunal perfusion. The endoluminal laser-Doppler technique was found to be easily applicable for continuous monitoring of jejunal perfusion, and the technique could prove valuable in detecting gastro-intestinal hypoperfusion in patients undergoing liver transplantation. |
| Databáze: | OpenAIRE |
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