Premorbid intellectual functioning and risk of schizophrenia and spectrum disorders

Autor:	Philip D. Harvey, Gad Lubin, Jonathan Rabinowitz, Mark Weiser, Haim Y. Knobler, Abraham Reichenberg, Michael Davidson, Asaf Caspi
Rok vydání:	2006
Předmět:	Male medicine.medical_specialty Adolescent Population Intelligence Severity of Illness Index Prodrome Cohort Studies Borderline intellectual functioning Risk Factors medicine Humans Risk factor education Psychiatry Problem Solving Intelligence Tests education.field_of_study Intelligence quotient medicine.disease Clinical Psychology Neuropsychology and Physiological Psychology Neurology Schizophrenia Population Surveillance Female Neurology (clinical) Psychology Cognition Disorders Psychosocial Cohort study
Zdroj:	Journal of clinical and experimental neuropsychology. 28(2)
ISSN:	1380-3395
Popis:	Evidence from longitudinal studies indicates that lower IQ score in childhood and early adolescence increases risk of schizophrenia and schizophrenia spectrum disorders (SSD). This study investigated the association between premorbid IQ and risk of SSD in a population-based cohort of 17-year-old conscripts. Fifty four thousand males assessed by the Israeli Draft Board during two consecutive years were followed by means of the Israeli National Psychiatric Hospitalization Case Registry for up to 11 years. Tests of verbal and non-verbal reasoning, mathematical knowledge and instructions comprehension and several psychosocial variables were recorded by the Draft Board. Risk for SSD increased with decreasing IQ score. Only poorer non-verbal reasoning conferred a significant increased risk for SSD after taking into account general intellectual ability. IQ was not associated with age of onset. These results confirm the importance of low intellectual functioning as a risk factor for SSD. This is unlikely to be due to prodrome.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383813c75f5dfd665c2b37339a17d0d8 https://pubmed.ncbi.nlm.nih.gov/16484093 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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