Relationship between birthweight and arterial elasticity in childhood
| Autor: | J A Pereira, Julicristie Machado de Oliveira, J O Lemos, Patrícia Helen de Carvalho Rondó, Luiz Roberto Innocente |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Blood Glucose
Male medicine.medical_specialty Waist medicine.medical_treatment Diastole Hemodynamics Nutritional Status Blood Pressure Gestational Age Cohort Studies Fetal Development Insulin resistance Internal medicine medicine Birth Weight Humans Child biology Anthropometry business.industry Insulin C-reactive protein Infant Newborn Gestational age General Medicine Arteries medicine.disease Elasticity Blood pressure Endocrinology C-Reactive Protein Cholesterol Socioeconomic Factors Child Preschool Radial Artery biology.protein Female Vascular Resistance Insulin Resistance business |
| Zdroj: | Clinical science (London, England : 1979). 115(10) |
| ISSN: | 1470-8736 |
| Popis: | There is a considerable debate about the potential influence of ‘fetal programming’ on cardiovascular diseases in adulthood. In the present prospective epidemiological cohort study, the relationship between birthweight and arterial elasticity in 472 children between 5 and 8 years of age was assessed. LAEI (large artery elasticity index), SAEI (small artery elasticity index) and BP (blood pressure) were assessed using the HDI/PulseWave™ CR-2000 CardioVascular Profiling System. Blood concentrations of glucose, total cholesterol and its fractions [LDL (low-density lipoprotein)-cholesterol and HDL (high-density lipoprotein)-cholesterol] and triacylglycerols (triglycerides) were determined by automated enzymatic methods. Insulin was assessed by a chemiluminescent method, insulin resistance by HOMA (homoeostasis model assessment) and CRP (C-reactive protein) by immunonephelometry. Two linear regression models were applied to investigate the relationship between the outcomes, LAEI and SAEI, and the following variables: birthweight, gestational age, glucose, LDL-cholesterol, HDL-cholesterol, triacylglycerols, insulin, CRP, HOMA, age, gender, waist circumference, per capita income, SBP (systolic BP) and DBP (diastolic BP). LAEI was positively associated with birthweight (P=0.036), waist circumference (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|