Clinical efficacy of transjugular intrahepatic portosystemic shunt in the treatment of hepatopulmonary syndrome

Autor: Zhenhua Fan, Lei Wang, Fuquan Liu, Zhendong Yue, Hongwei Zhao, Fu-Liang He
Rok vydání: 2017
Předmět:
Zdroj: Medicine
ISSN: 0025-7974
DOI: 10.1097/md.0000000000009080
Popis: Transjugular intrahepatic portosystemic shunt (TIPS) reduces the portal venous pressure of patients with hepatopulmonary syndrome (HPS). To describe the patients who underwent TIPS for the treatment of HPS. A retrospective study was performed on 81 patients with HPS and gastrointestinal hemorrhage treated with TIPS. Thirty patients underwent TIPS through the main portal vein (group A), 24 through the left branch of the portal vein (group B), and 27 through the right branch of the portal vein (group C). The partial pressure of arterial oxygen (PaO2), alveolar-to-arterial oxygen partial pressure gradient (A–aPO2), oxygen saturation (SO2), and complications were recorded and compared. The survival rate for each group was calculated. The technical success rate was 100% in the 3 groups. Preoperative portal vein pressure showed no significant differences between the 3 groups, which was decreased post-TIPS operation. In group A, PaO2 and SO2 were higher in 15 days and 3 months postoperative than preoperative (P .05), whereas A–aPO2 decreased at 3 months (P = .041) than preoperative. In group B, all indicators at each follow-up time point after TIPS were improved significantly as compared with the preoperative group (P
Databáze: OpenAIRE