Calmitine: A calcium-binding mitochondrial protein specific for fast-twitch muscle fibers

Autor: Brigitte Lucas-Heron, Nelly Schmitt, Béatrice Ollivier
Rok vydání: 1990
Předmět:
Zdroj: Neuroscience Letters. 115:103-107
ISSN: 0304-3940
DOI: 10.1016/0304-3940(90)90525-e
Popis: Mitochondrial fractions were isolated from fast-twitch (EDL), slow-twitch (soleus) and heart muscle of normal rat (WKY). Protein separation by electrophoresis and study of calcium-45 binding showed that a specific calcium protein (designated as calmitine) was present in the mitochondria of fast-twitch muscle but practically inexistent in slow-twitch and cardiac muscle. It seems to be related to calcium uptake by an energy-dependent mechanism.
Databáze: OpenAIRE