Discontinuing antidepressants: Pearls and pitfalls

Autor:	Samantha J, Zwiebel, Adele C, Viguera
Rok vydání:	2022
Předmět:	Humans Paresthesia General Medicine Antidepressive Agents
Zdroj:	Cleveland Clinic Journal of Medicine. 89:18-26
ISSN:	1939-2869 0891-1150
Popis:	Stopping antidepressants can be challenging due to the high rate of discontinuation symptoms. Patients with antidepressant discontinuation syndrome (ADS) commonly experience insomnia, flu-like symptoms, mood disturbances, dizziness, and paresthesias, but a broad array of adverse effects is possible. Symptoms can last for days to months, and different symptoms have different durations. Patient education, identification of patients most at risk for developing symptoms, and a slow antidepressant taper or cross-taper are important steps in mitigating the risk of ADS and managing patient concerns about ADS. Tapers should be carried out over weeks to months. Discontinuation symptoms should be managed with restarting the prior dose of antidepressant and then tapering even more slowly, with additional symptomatic management as needed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382bf8572c79d9aa0cd22eb080d80360 https://doi.org/10.3949/ccjm.89a.21020 Zobrazit plný text záznamu