Phytate technetium-99m versus dextran 500 technetium-99m in the sentinel lymph node biopsy
| Autor: | Jairo Wagner, Geruza Rezende Paiva, Y. Juliano, N.F. Novo, Renato Santos de Oliveira Filho, S. A. Nogueira, João Lorenzo Bidart Sampaio Rocha, Lydia Masako Ferreira |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Pathology medicine.medical_specialty Phytic Acid Sentinel lymph node chemistry.chemical_element Technetium Blood substitute chemistry.chemical_compound Biopsy Animals Medicine Tissue Distribution Radiology Nuclear Medicine and imaging Radionuclide imaging Rats Wistar Radionuclide Imaging Biopsy procedure Radiological and Ultrasound Technology medicine.diagnostic_test Sentinel Lymph Node Biopsy business.industry Dextrans General Medicine Rats Dextran chemistry Lymph Nodes Radiopharmaceuticals business Nuclear medicine Technetium-99m |
| Zdroj: | Acta Radiologica. 47:65-70 |
| ISSN: | 1600-0455 0284-1851 |
| DOI: | 10.1080/02841850500406803 |
| Popis: | Purpose: To study which of the two most used radiopharmaceutical drugs for the sentinel lymph node (SLN) biopsy procedure (dextran 500 99mTc and phytate 99mTc) best defines the SLN and migrates less to other lymph nodes. Material and Methods: Thirty-two rats, separated into two groups, underwent lymphoscintigraphy examination with either dextran or phytate followed by sentinel (popliteal), lumbar, and inguinal lymph node biopsy. Radiation was detected with a gamma probe. Results: The statistical study indicated count rates significantly higher in the SLN than in the other basins for both the dextran ( P Conclusion: There was no statistically significant difference between dextran and phytate in the SLN identification, but the phytate migrated to fewer lymphatic basins beyond the SLN and with less intensity. |
| Databáze: | OpenAIRE |
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