Cryoablation of goiter irrespective of thyroid profile
| Autor: | Mohamed Reda Halawa, Nihad A. Ibrahim, Sherif Z Mansour, Ashraf Z Ghoneim, Mohamed E S Hamed, Ahmed Bahaaeldin |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Thyroid nodules
medicine.medical_specialty Goiter medicine.medical_treatment 030209 endocrinology & metabolism Cryotherapy Thyroid function tests Cryosurgery 03 medical and health sciences 0302 clinical medicine medicine General Environmental Science medicine.diagnostic_test business.industry Ultrasound Thyroid Cryoablation Nodule (medicine) General Medicine medicine.disease Surgery medicine.anatomical_structure 030220 oncology & carcinogenesis General Earth and Planetary Sciences medicine.symptom business Hormone |
| Zdroj: | QJM: An International Journal of Medicine. 113 |
| ISSN: | 1460-2393 1460-2725 |
| DOI: | 10.1093/qjmed/hcaa052.050 |
| Popis: | Background Thyroid nodules are extremely common. By age 60, about one-half of all people have a thyroid nodule. Cryoablation is used in a variety of clinical applications, using hollow needles (cryoprobes). Cryoprobes are inserted into or placed adjacent to diseased tissue which is desired to be ablated. Aim of work To evaluate the effect of Cryoablation on the size & function of thyroid noduleWhich may replace the need for surgery or radiotherapy. Patients & methods This is an interventional therapeutic study, conducted in Ain-Shams University hospitals; endocrinology clinic. Our study sample included 80 subjects, age between 20 & 60, having thyroid nodule diagnosed by ultrasound. Subjects were divided into 2 groups: Group 1 included 40 subjects “control group” who were not subjected to cryoablation. Group 2 included 40 subjects “cases” upon which cryoablation was done. Neck ultrasound was done for subjects & they were sampled for their TSH, free T4 & free T3 levels at start and after 3 & 6 months. Results There was high statistical significant difference between group 1 & group 2 regarding nodule size after 6 months. Group 1 showed mean nodule size (0.89 cm ± 0.25 SD) while group 2 showed (0.62 cm ± 0.35 SD),(p-value Conclusions Cryoablation causes nodule size reduction, especially after 2nd session. Cryoablation doesn’t affect thyroid function tests, all through our study. |
| Databáze: | OpenAIRE |
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