Unique hepatic imaging features in a patient with nodular regenerative hyperplasia of the liver associating with systemic lupus erythematosus
| Autor: | S K Kei, I S C Luk, W L Ng, Tony K. L. Loke, W H Chan, T N Chau, Vincent K S Leung |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Pathology medicine.medical_specialty 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Rheumatology Fibrosis Hypertension Portal medicine Humans Lupus Erythematosus Systemic Ultrasonography 030203 arthritis & rheumatology Purpura Thrombocytopenic Idiopathic Hyperplasia Lupus erythematosus medicine.diagnostic_test business.industry Liver Diseases Magnetic resonance imaging medicine.disease Magnetic Resonance Imaging Liver regeneration Liver Regeneration Liver Portal hypertension Female Tomography X-Ray Computed Complication business Nodular regenerative hyperplasia |
| Zdroj: | Lupus. 16:205-208 |
| ISSN: | 1477-0962 0961-2033 |
| DOI: | 10.1177/09612033707076513 |
| Popis: | Nodular regenerative hyperplasia (NRH) of the liver, characterized by regenerative nodules distributed throughout the liver in the absence of fibrosis, is a rare but important complication of systemic lupus erythematosus (SLE). The main consequence of NRH is non-cirrhotic portal hypertension. We describe a female patient who had immune thrombocytopenia in association with elevated liver enzymes and evidence of portal hypertension as initial manifestations of SLE. Computed tomographic scan and magnetic resonance imaging of the liver in this patient showed enhancing periportal tubular structures distributed throughout the liver. The diagnosis of NRH was eventually disclosed by transcutaneous needle liver biopsy. The pattern of radiological abnormality in this patient has not been described previously in NRH. In addition, we believe this is a first reported case of SLE presenting with immune thrombocytopenia in association with NRH. |
| Databáze: | OpenAIRE |
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