Supplementary figures from PI3K Positively Regulates YAP and TAZ in Mammary Tumorigenesis Through Multiple Signaling Pathways
Autor: | Xiaolong Yang, Christopher Nicol, Eric Asselin, Sandip SenGupta, Yawei Hao, Elizabeth Lightbody, Taha Azad, Tess Montminy, Yulei Zhao |
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Rok vydání: | 2023 |
DOI: | 10.1158/1541-7786.22513593.v1 |
Popis: | Figure. 1 PIK3CB positively regulates TAZ. S-Figure. 2 Quantitation of subcellular localization of YAP and TAZ. S-Figure 3. PDK1 regulates LATS-YAP/TAZ through its kinase activity. S-Figure 4. No direct regulations between LATS and AKT. S-Fig. 5 AKT1 positively regulates YAP expression which is involved in YAP-LATS negative feedback. S-Figure 6. A-B. YAP and TAZ were knocked out through CRISPR system in MCF10A-PIK3CB or PIK3CA-H1047R cells |
Databáze: | OpenAIRE |
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