Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies
| Autor: | Khaled Ezzedine, Jérôme Rambert, Daniel Moynet, Maria Mamani-Matsuda, Marie-Catherine Receveur, Thierry Pistone, Brigitte Autran, Denis Malvy, Hugues Tolou, Djavad Mossalayi |
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| Přispěvatelé: | Service de médecine interne et maladies tropicales, CHU Bordeaux [Bordeaux]-Groupe hospitalier Saint-André, Centre René Labusquière, Université Sciences et Technologies - Bordeaux 1, Parasitologie/Médicaments (PPF), Université Bordeaux Segalen - Bordeaux 2, Immunité et Infection, Université Pierre et Marie Curie - Paris 6 (UPMC)-IFR113-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de Médecine Tropicale du Service de Santé des Armées (IMTSSA), Service de Santé des Armées, Université Sciences et Technologies - Bordeaux 1 (UB), BMC, Ed. |
| Jazyk: | angličtina |
| Předmět: |
Male
medicine.medical_specialty viruses Arthritis Case Report Antibodies Viral medicine.disease_cause lcsh:Infectious and parasitic diseases 03 medical and health sciences 0302 clinical medicine Medical microbiology [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases Humans Medicine lcsh:RC109-216 Chikungunya Alphavirus infection MESH: Alphavirus Infections 030304 developmental biology 030203 arthritis & rheumatology Arthritis Infectious 0303 health sciences Tenosynovitis MESH: Humans MESH: Middle Aged biology Alphavirus Infections business.industry virus diseases MESH: Chikungunya virus Middle Aged medicine.disease Virology MESH: Immunoglobulin M MESH: Male 3. Good health Destructive Arthritis Infectious Diseases Immunoglobulin M Immunology biology.protein [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases MESH: Arthritis Infectious business Chikungunya virus Rheumatism MESH: Antibodies Viral |
| Zdroj: | BMC Infectious Diseases BMC Infectious Diseases, BioMed Central, 2009, 9 (1), pp.200. ⟨10.1186/1471-2334-9-200⟩ BMC Infectious Diseases, 2009, 9 (1), pp.200. ⟨10.1186/1471-2334-9-200⟩ BMC Infectious Diseases, Vol 9, Iss 1, p 200 (2009) |
| ISSN: | 1471-2334 |
| DOI: | 10.1186/1471-2334-9-200 |
| Popis: | Background Chikungunya fever is an emerging arboviral disease characterized by an algo-eruptive syndrome, inflammatory polyarthralgias, or tenosynovitis that can last for months to years. Up to now, the pathophysiology of the chronic stage is poorly understood. Case presentation We report the first case of CHIKV infection with chronic associated rheumatism in a patient who developed progressive erosive arthritis with expression of inflammatory mediators and persistence of specific IgM antibodies over 24 months following infection. Conclusions Understanding the specific features of chikungunya virus as well as how the virus interacts with its host are essential for the prevention, treatment or cure of chikungunya disease. |
| Databáze: | OpenAIRE |
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