PEGylated amphiphilic polymeric manganese(II) complexes as magnetic resonance angiographic agents

Autor:	Xiaoqin Liu, Shengxiang Fu, Chunchao Xia, Mengye Li, Zhongyuan Cai, Changqiang Wu, Fulin Lu, Jiang Zhu, Bin Song, Qiyong Gong, Hua Ai
Rok vydání:	2022
Předmět:	Manganese Magnetic Resonance Spectroscopy Biomedical Engineering Contrast Media Humans General Materials Science General Chemistry General Medicine Magnetic Resonance Imaging Polyethylene Glycols
Zdroj:	Journal of materials chemistry. B. 10(13)
ISSN:	2050-7518
Popis:	Currently, the most commonly used clinical magnetic resonance imaging (MRI) contrast agents, Gd(III) chelates, have been found to be associated with nephrogenic systemic fibrosis (NSF) in renally compromised patients. Toxicity concerns related to Gd(III)-based agents prompted intensive research toward the development of safe, efficient, and long-cycle non-Gd contrast agents. Herein, three amphiphilic polymeric manganese (Mn) ligands (mPEG
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381b82d5579941be7b573e2d3e49ce65 https://pubmed.ncbi.nlm.nih.gov/35284914 Zobrazit plný text záznamu