Plasma fluctuation in estradiol-17β and bone resorption markers around parturition in dairy cows
| Autor: | Saori Sato, Takeshi Osawa, Bhuminad Devkota, Masahiro Takahashi, Norio Yamagishi, Kouya Sasaki, Atsushi Ueki |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
tartrate-resistant acid phosphatase isoform 5b (TRAP5b) Acid Phosphatase chemistry.chemical_element Parathyroid hormone Calcium Bone resorption Collagen Type I Hydroxyproline chemistry.chemical_compound Internal medicine medicine Internal Medicine Animals Estradiol 17β Bone Resorption Tartrate-resistant acid phosphatase General Veterinary biology Estradiol Chemistry Tartrate-Resistant Acid Phosphatase dairy cow Acid phosphatase Parturition Plasma levels Note osteoclast-mediated bone resorption osteocytic remodeling Isoenzymes Endocrinology Parathyroid Hormone biology.protein Cattle Female Peptides Biomarkers |
| Zdroj: | The Journal of Veterinary Medical Science |
| ISSN: | 1347-7439 0916-7250 |
| Popis: | Blood samples were obtained sequentially from 10 dairy cows around the time of parturition to assess plasma fluctuations in estradiol-17β (E2) levels in association with those of several bone resorption markers. Plasma E2 concentration increased sharply a few days prepartum and decreased quickly after parturition. In terms of bone resorption markers, the plasma level of tartrate-resistant acid phosphatase isoform 5b (TRAP5b) rose significantly, commencing 1 week prepartum, and was maintained at this level to a few days postpartum. The plasma concentration of carboxyterminal collagen cross-links of type-I collagen (CTx) increased significantly after parturition. These observations suggest that osteoclast-mediated bone resorption was activated after parturition when plasma E2 concentrations decreased. |
| Databáze: | OpenAIRE |
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