Action of phosphorylated mannanoligosaccharides on immune and hematological responses and fecal consistency of dogs experimentally infected with enteropathogenic Escherichia coli strains
| Autor: | Marilene Rodrigues Chang, R.A.C. Corrêa, Eliana Maria Ferreira Gouveia, Iandara Schettert Silva, V.J.V. Onselem, Flábio R. Araújo, Gerson Nakazato |
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| Přispěvatelé: | Programa de Pós-Graduação em Saúde e Desenvolvimento para a Região Centro-Oeste, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Departamento de Microbiologia, Universidade Estadual de Londrina, Londrina, PR, Departamento de Cirurgia, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil, FLABIO RIBEIRO ARAUJO, CNPGC, Programa de Pós-Graduação em Saúde e Desenvolvimento para a Região Centro-Oeste, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil. |
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Immunoglobulin A
Diarrhea dogs Chemical Phenomena Phosphorylated 31 mannanoligo - saccharides Enteropathogenic E. coli lcsh:QR1-502 Oligosaccharides In vivo experiment medicine.disease_cause Microbiology Immunoglobulin G lcsh:Microbiology Enteropathogenic Escherichia coli Feces Immune system Gastrointestinal Agents medicine Escherichia coli Leukocytes enteropathogenic E. coli Animals Gastrointestinal agent biology Antibodies Bacterial in vivo experiment Disease Models Animal Blood Prebiotics PCR phosphorylated 31 mannanoligosaccharides Immunology biology.protein phosphorylated 31 mannanoligo saccharides medicine.symptom Research Paper |
| Zdroj: | Brazilian Journal of Microbiology, Vol 44, Iss 2, Pp 499-504 (2013) Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice) Empresa Brasileira de Pesquisa Agropecuária (Embrapa) instacron:EMBRAPA Brazilian Journal of Microbiology Brazilian Journal of Microbiology, Volume: 44, Issue: 2, Pages: 499-504, Published: 2013 Brazilian Journal of Microbiology v.44 n.2 2013 Sociedade Brasileira de Microbiologia (SBM) instacron:SBM |
| ISSN: | 1678-4405 |
| Popis: | The therapeutic action of phosphorylated mannanoligosaccharides (MOS) was investigated regarding its prebiotic activity on enteropathogenic Escherichia coli (EPEC). Diarrhea was induced in dogs by experimental infection with EPEC strains. Then MOS was supplied once a day, in water for 20 days. Immunological (IgA and IgG), hematological (lymphocytes, neutrophils and monocytes) and bacteriological variables (PCR detection of the eae gene of EPEC recovered from stool culture), as well as occurrence of diarrhea were evaluated. All strains caused diarrhea at 24, 48 and 72 h after infection. PCR results indicated that E. coli isolated from stool culture of all infected animals had the eae gene. There was no significant difference among groups as to number of blood cells in the hemogram and IgA and IgG production. MOS was effective in recovering of EPEC-infected dogs since prebiotic-treated animals recovered more rapidly from infection than untreated ones (p < 0.05). This is an important finding since diarrhea causes intense dehydration and nutrient loss. The use of prebiotics for humans and other animals with diarrhea can be an alternative for the treatment and prophylaxis of EPEC infections. |
| Databáze: | OpenAIRE |
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