Myocardial structure and vascularization of hypertrophied hearts
| Autor: | Toshio Nakamura, Atsushi Machida, Shigeru Arai |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Heart Ventricles Concentric hypertrophy Cardiomegaly Concentric General Biochemistry Genetics and Molecular Biology Muscle hypertrophy Internal medicine Medicine Humans Child Aged business.industry Myocardium Infant General Medicine Blood flow Anatomy Organ Size Middle Aged Coronary Vessels Capillaries Coronary arteries medicine.anatomical_structure Capillary length Cardiac hypertrophy Child Preschool Cardiology Female business Mathematics Artery |
| Zdroj: | The Tohoku journal of experimental medicine. 95(1) |
| ISSN: | 0040-8727 |
| Popis: | The growth of the coronary artery and the myocardial capillarization in hypertrophied hearts were quantitatively evaluated in reference to myocardial volume. In concentric hypertrophy the mean blood flow per unit volume of the heart muscle estimated by the anatomical radii of the three major branches of coro-nary arteries was practically the same as that in the normal heart. A harmonious growth of the coronary artery with increasing myocardial volume was accordingly concluded. The often asserted view that hypertrophied hearts are subject to coronary insufficiency on account of undergrowth of coronary arteries inherent to cardiac hypertrophy was not supported. The total capillary length was found increased in hypertrophied hearts in parallel with the increase of the total surface area of the muscle fibers. However, the capillary length per unit volume of the heart muscle was reduced in hypertrophied hearts. Histometrical treatments revealed that the configuration of individual heart muscle fibers in concentric hypertrophy was geometrically similar to that in the normal heart. The behavior of the muscle fiber was essentially the same in dilata-tory hypertrophy too, although the growth in length predominated over that in breadth in a small number of cases. A growth in breadth of the muscle fibers not accompanied by one in length did not take place even in concentric hypertrophy. The difference of concentric and dilatatory hypertrophies was sought consequently in different structural arrangement and not in the shape of heart muscle fibers in the myocardial layer. |
| Databáze: | OpenAIRE |
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