A Multidisciplinary Approach to the Management of Fibrolamellar Carcinoma: Current Perspectives and Future Prospects

Autor:	Georgios Polychronidis, Anastasia Murtha-Lemekhova, Juri Fuchs, Evdokia Karathanasi, Katrin Hoffmann
Rok vydání:	2022
Předmět:	Oncology Pharmacology (medical)
Zdroj:	OncoTargets and Therapy. 15:1095-1103
ISSN:	1178-6930
DOI:	10.2147/ott.s296127
Popis:	Fibrolamellar carcinoma (FLC) is a rare primary liver tumor affecting predominantly younger and otherwise healthy patients. Typically, FLC presents with advanced disease due to the paucity of typical symptoms and no history of underlying liver disease. Depending on tumor characteristics and the patient's general condition, surgical treatment is the most promising treatment modality. Aggressive resection and liver transplantation have been utilized and are presently indispensable curative treatment options. Under certain circumstances surgical resection is also possible for metachronous metastases or local recurrence. Recent tumor biology discoveries have contributed to improved diagnostic specificity and systemic treatment options.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3803cebc9eea5bce5dd0cc7020af96f0 https://doi.org/10.2147/ott.s296127 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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