Remineralizing potential of dental composites containing silanized silica-hydroxyapatite (Si-HAp) nanoporous particles charged with sodium fluoride (NaF)
Autor: | André L. Rossi, Dirciane Perpétuo Reis, Eduardo Moreira da Silva, Maristela Barbosa Portela, Aline de Almeida Neves, Jaime Dutra Noronha Filho |
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Rok vydání: | 2019 |
Předmět: |
Dental composite
Dental Caries Nanopores 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine stomatognathic system Flexural strength Sodium fluoride Humans 030212 general & internal medicine Composite material Dental Enamel Tooth Demineralization General Dentistry Enamel paint Nanoporous 030206 dentistry Silicon Dioxide stomatognathic diseases Durapatite chemistry Tooth Remineralization Silanization visual_art Knoop hardness test visual_art.visual_art_medium Sodium Fluoride Particle Hydroxyapatites |
Zdroj: | Journal of Dentistry. 90:103211 |
ISSN: | 0300-5712 |
DOI: | 10.1016/j.jdent.2019.103211 |
Popis: | Objectives To synthesize and evaluate the enamel remineralizing potential of dental composites containing silanized silica-hydroxyapatite (Si-HAp) nanoporous particles charged with sodium fluoride (NaF). Methods Si-HAp particles were synthesized using a solid-state method. Dental composites were prepared by incorporating 70 wt.% of Si-HAp particles into a 70/30 wt.% Bis-GMA/TEGDMA organic matrix. Four dental composites were produced: SilF, Sil, F, and NT (nontreated). For SilF and F, Si-HAp particles were previously treated with 10% NaF (F). Afterwards, SilF and Sil composites had their particles silanized (Sil) with α-methacryloxypropyl-1-trimethoxysilane (α-MPS). The remineralizing potential was evaluated in caries-like enamel lesions induced byS. mutans biofilm for seven days and after pH-cycling for fifteen days using X-ray microtomography (micro-CT). Z350 was used as a commercial control for remineralizing potential evaluation Degree of conversion (DC%), flexural strength (FS), and Knoop hardness (KHN) were characterized. Data were analyzed using one-way ANOVA and Tukey’s HSD post-hoc test (α = 0.05). Results F presented the highest enamel remineralizing potential, followed by SilF. Alternatively, Sil and NT were not capable of totally recovering the enamel mineral loss. NT showed the highest DC%, followed by Sil, F, and SilF. Sil and NT showed the highest FS when compared to SilF and F. No statistical significance in KHN was found among the composites. Conclusions Dental composites with Si-HAp nanoporous particles charged with NaF presented a remineralizing potential for human enamel. However, this ability underwent a subtle reduction after particle silanization. Clinical significance Si-HAp nanoporous particles charged with NaF may be an alternative for producing dental composites with an improved remineralizing potential for enamel affected by caries. |
Databáze: | OpenAIRE |
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