T-cell post-transplantation lymphoproliferative disorders after cardiac transplantation: a single institutional experience
| Autor: | Hediya Y Draoua, Bachir Alobeid, Donna Mancini, Lawrence Tsao, Linda J. Addonizio, Govind Bhagat |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Adult
Graft Rejection Male medicine.medical_specialty Pathology Heart Diseases Lymphoproliferative disorders Lymphoma T-Cell medicine.disease_cause Herpesviridae Internal medicine medicine Humans T-cell lymphoma Aged Hematology business.industry Middle Aged medicine.disease Epstein–Barr virus Lymphoma Transplantation surgical procedures operative Heart Transplantation Female business Complication Immunosuppressive Agents |
| Zdroj: | British Journal of Haematology. 127:429-432 |
| ISSN: | 0007-1048 |
| DOI: | 10.1111/j.1365-2141.2004.05212.x |
| Popis: | Post-transplantation lymphoproliferative disorders (PTLDs) are a well-recognized and potentially life-threatening complication of solid organ transplantation. While the vast majority of PTLDs are B-cell lymphoproliferations, T-cell PTLDs are rarely seen. Among 898 patients receiving cardiac transplants between 1990 and 2003, 34 patients (3.8%) developed PTLDs with two (0.2%) T-cell PTLDs, 31 (3.5%) B-cell PTLDs and one (0.1%) natural killer cell PTLD. An additional three cases of T-cell PTLD were identified among all cardiac transplant patients followed at our institution. These T-cell PTLDs comprised a heterogeneous group of Epstein-Barr virus negative lymphoproliferations that developed late after transplantation and followed an aggressive course. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text