Multilocus Genotypic Analysis of Cryptosporidium parvum Isolates from Different Hosts and Geographical Origins
| Autor: | Sylvie M. Le Blancq, Una M. Morgan, Saul Tzipori, Andrea Crisanti, Lorenza Putignani, Giovanni Widmer, Furio Spano, Pina Sallicandro, Laurie Tchack |
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| Rok vydání: | 1998 |
| Předmět: |
Genetic Markers
Microbiology (medical) Genotype Genes Protozoan Cryptosporidiosis Biology Polymerase Chain Reaction Genetic analysis Apicomplexa Feces parasitic diseases Animals Humans DNA Primers Cryptosporidium parvum Genetics Molecular Epidemiology Polymorphism Genetic Base Sequence Molecular epidemiology Host (biology) Australia DNA Protozoan South America biology.organism_classification Europe Genetic marker North America Parasitology Restriction fragment length polymorphism Polymorphism Restriction Fragment Length |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1098-660X 0095-1137 |
| DOI: | 10.1128/jcm.36.11.3255-3259.1998 |
| Popis: | The genetic analysis of oocysts recovered from the stools of humans and animals infected with Cryptosporidium parvum has consistently shown the existence of two distinct genotypes. One of the genotypes is found exclusively in some human infections, whereas the other genotype is found in human as well as in animal infections. On the basis of these observations and the results of published epidemiological studies with single polymorphic markers, the existence of two separate transmission cycles has been postulated, one exclusively anthroponotic and the other involving both animals and humans. To test this hypothesis, C. parvum isolates of different geographic and host origins were analyzed by using unlinked genetic polymorphisms. A total of 28 isolates originating from Europe, North and South America, and Australia were examined. Isolates clustered into two groups, one comprising both human and animal isolates and the other comprising isolates only of human origin. The absence of recombinant genotypes is consistent with two reproductively isolated populations within the species C. parvum. |
| Databáze: | OpenAIRE |
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