MEN 2B masquerading as chronic blepharitis and euryblepharon

Autor:	Ralph C. Eagle, Jacqueline R. Carrasco, Alison B. Huggins
Rok vydání:	2019
Předmět:	Male medicine.medical_specialty Adolescent medicine.medical_treatment Multiple Endocrine Neoplasia Type 2b Eyelid Neoplasms Pheochromocytoma Cornea 03 medical and health sciences Neuroma 0302 clinical medicine Tongue Biopsy medicine Humans Thyroid Neoplasms Trigeminal Nerve Family history 030223 otorhinolaryngology Multiple endocrine neoplasia Retrospective Studies Blepharitis medicine.diagnostic_test business.industry Thyroidectomy Eyelids medicine.disease Dermatology Carcinoma Neuroendocrine Ophthalmology medicine.anatomical_structure Chronic Disease 030221 ophthalmology & optometry Eyelid business Multiple endocrine neoplasia type 2b
Zdroj:	Orbit (Amsterdam, Netherlands). 38(6)
ISSN:	1744-5108
Popis:	This is a retrospective case description of a single male patient found to have multiple endocrine neoplasia syndrome type 2B (MEN 2B). At the age of 14, he presented for evaluation of ocular irritation and eyelid thickening. Intraoperative assessment revealed mucosal lesions on the anterior dorsum of his tongue and biopsy of multiple eyelid lesions disclosed bilateral submucosal neuromas, leading to the diagnosis of MEN 2B. MEN 2B is a potentially life-threatening syndrome due to the risk of developing medullary thyroid carcinoma (MTC) and pheochromocytoma. The patient was found to have MTC requiring thyroidectomy. We hope to highlight the clinical and histopathologic findings of MEN 2B in an effort to emphasize the importance of its identification in the absence of a family history.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37fb3601c198ceb24a6aeff8764fdf07 https://pubmed.ncbi.nlm.nih.gov/30688132 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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