Aging, vascular risk, and cognition: Blood glucose, pulse pressure, and cognitive performance in healthy adults
| Autor: | Cheryl L. Dahle, Bradley S. Jacobs, Naftali Raz |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Blood Glucose Male Gerontology Aging medicine.medical_specialty Adolescent Psychometrics Social Psychology Hemodynamics Blood sugar Blood Pressure Neuropsychological Tests Article Young Adult Reference Values Risk Factors Internal medicine Diabetes mellitus Reaction Time medicine Humans Effects of sleep deprivation on cognitive performance Aged Arterial pulse pressure Age Factors Association Learning Cognition Middle Aged medicine.disease Pulse pressure Memory Short-Term Blood pressure Diabetes Mellitus Type 2 Cardiovascular Diseases Hypertension Mental Recall Cardiology Female Geriatrics and Gerontology Cognition Disorders Psychology |
| Zdroj: | Psychology and Aging. 24:154-162 |
| ISSN: | 1939-1498 0882-7974 |
| DOI: | 10.1037/a0014283 |
| Popis: | Advanced age is associated with decline in many areas of cognition as well as increased frequency of vascular disease. Well-described risk factors for vascular disease, such as diabetes and arterial hypertension, have been linked to cognitive deficits beyond those associated with aging. To examine whether vascular health indices such as fasting blood glucose levels and arterial pulse pressure can predict subtle deficits in age-sensitive abilities, the authors studied 104 healthy adults (ages 18 to 78) without diagnoses of diabetes or hypertension. Whereas results revealed a classic pattern of age-related differences in cognition, preprandial blood glucose level and pulse pressure independently and differentially affected cognitive performance. High-normal blood glucose levels were associated with decreased delayed associative memory, reduced accuracy of working memory processing among women, and slower working memory processing among men. Elevated pulse pressure was associated with slower perceptual-motor processing. Results suggest that blood glucose levels and pulse pressure may be sensitive indicators of cognitive status in healthy adults; however, longitudinal research is needed to determine whether such relatively mild elevations in this select group predict age-related cognitive declines. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|