Inhaled corticosteroids may have a protective effect against coronavirus infection
| Autor: | Cristina Crespo Soto, Angela Moro Simón, Aurora Sacristán Salgado, Marta Cano Pazos, Javier Visa Caño, Edgardo Raul Lowell, Joaquín Rodriguez Fra, Daniel Ramos Pollo, Alicia Armentia, Sara García Vaquero, Jesús Galán de la Calle, Juan Claudio Navarro Cañadas, Álvaro Sanz Rubiales, Blanca Martín-Armentia, Sara Fernández Cortés, Carmen Sánchez Toledano, Sara Martín-Armentia |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Allergy Adolescent Coronavirus disease 2019 (COVID-19) Cross-sectional study Immunology Inhaled corticosteroids medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Adrenal Cortex Hormones Internal medicine Administration Inhalation medicine Humans Immunology and Allergy Respiratory system Aged Coronavirus Aged 80 and over business.industry Medical record COVID-19 General Medicine Middle Aged Prognosis medicine.disease Asthma Nursing Homes Cross-Sectional Studies 030228 respiratory system Spain COVID-19 Nucleic Acid Testing Female Nursing homes business 030215 immunology |
| Zdroj: | Allergologia et Immunopathologia. 49:113-117 |
| ISSN: | 0301-0546 |
| Popis: | Background: Spain has been severely affected by the COVID-19 epidemic, with 195,944 persons infected and 20,453 deaths at the time of writing. Older people with respiratory or cardiac conditions are most at risk. Objective: The aim was to compare respiratory symptoms in nursing home residents and patients with uncontrolled asthma, who are considered vulnerable to COVID-19. Methods: We studied 134 nursing home residents and 139 patients with uncontrolled asthma, groups vulnerable to COVID-19. Demographic characteristics, clinical manifestations, outcomes, key laboratory results, and radiological images were collected from medical records. COVID-19 infection was detected by polymerase chain reaction (PCR). Results: Thirteen (9.3%) patients with uncontrolled asthma, all receiving inhaled corticosteroids were infected by COVID-19. Eighty (60%) nursing home residents were infected; only 28, all of whom had received inhaled corticosteroids, had a good prognosis. Conclusions: Early treatment with inhaled corticosteroids may be helpful in COVID-19 infection. Persons with an allergy might have some protective mechanisms against coronavirus. |
| Databáze: | OpenAIRE |
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