Clinical value of procalcitonin in critically ill patients infected by SARS-CoV-2
| Autor: | Pitter Cueto, Armando Pinos, Anna Hernández-Aguilera, Ana Parra, Pedro Garrido, Conxita Rovira, Manuel Sosa, Elisabet Garcia, Raquel Enriquez, Immaculada Vallverdú |
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| Rok vydání: | 2021 |
| Předmět: |
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medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Critical Illness medicine.medical_treatment Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Article Procalcitonin 03 medical and health sciences Patient Admission 0302 clinical medicine Humans Medicine Pandemics Aged Retrospective Studies Aged 80 and over Mechanical ventilation Critically ill business.industry COVID-19 030208 emergency & critical care medicine General Medicine Emergency department Middle Aged Intensive Care Units Spain Emergency medicine Emergency Medicine Clinical value Female Emergency Service Hospital business Biomarkers Cohort study |
| Zdroj: | The American Journal of Emergency Medicine |
| ISSN: | 0735-6757 |
| DOI: | 10.1016/j.ajem.2020.11.011 |
| Popis: | Background Blood procalcitonin (PCT) levels usually increase during infectious diseases and might be helpful to differentiate bacterial from non-bacterial origin. COVID-19 patients could present co-infections at initial presentation in the Emergency Department and nosocomial infections during stay in the ICU. However, the published literature has not established whether PCT changes could aid in the diagnosis of infectious complication during the COVID-19 pandemic. Methods Retrospective, single-center, cohort study, including COVID-19 patients admitted between March and May 2020. The data were prospectively collected for department purposes; laboratory results were collected automatically at admission and during the whole patient admission. Results 56 patients were analyzed (female 32%, male 68%), 35 were admitted to ICU, and 21 received general ward care. 21 ICU patients underwent mechanical ventilation (88%), and 9 died during admission (26%). Non-survivors had higher initial blood PCT levels than survivors at ICU admission (p. |
| Databáze: | OpenAIRE |
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