Pathologic laughter and crying in ALS: a search for their origin
| Autor: | J. P. Gallagher |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Adult
Male endocrine system Pediatrics medicine.medical_specialty Pseudobulbar affect Adolescent media_common.quotation_subject Neurocognitive Disorders Disease Crying Dextromethorphan/Quinidine Developmental psychology Laughter medicine Humans Affective Symptoms Amyotrophic lateral sclerosis Pathological media_common Amyotrophic Lateral Sclerosis General Medicine Middle Aged medicine.disease Neurology Tears Female Neurology (clinical) medicine.symptom Psychology medicine.drug |
| Zdroj: | Acta neurologica Scandinavica. 80(2) |
| ISSN: | 0001-6314 |
| Popis: | Spells of laughter and crying are well known in patients with amyotrophic lateral sclerosis (ALS). Since ALS occurs mostly in older age groups, this brings up the possibility that aging changes in the brain could play a causative role in the origin of such spells. To rule out or at least reduce the complicating factor of aging, a study was made of the incidence of pathologic laughter and crying in patients whose motor neuron disease had started before the age of 45 years. The data were collected from 73 such individuals, all with confirmed ALS. All told, 36 had experienced episodes of pathologic laughter and/or crying. Of these, 20 had bouts of both laughter and crying. 9 bouts of crying alone and 7 spells of laughter alone. Nearly all with such emotional spells had developed bulbar involvement with the illness. The youngest patient with spells was 31 when his illness began and 35 when he started to have bouts of crying. |
| Databáze: | OpenAIRE |
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