RETAINED, NONDISSOLVING, TUBULAR FOREIGN BODIES IN THE VITREOUS CAVITY AFTER INTRAVITREAL DEXAMETHASONE (OZURDEX) IMPLANTATION
| Autor: | Alec L Amram, Ian C. Han, D. Brice Critser, James C. Folk |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Choroiditis Eye Diseases Article Dexamethasone Vitreous cavity 03 medical and health sciences 0302 clinical medicine Chart review Panuveitis medicine Humans Glucocorticoids Foreign Bodies Retrospective Studies 030304 developmental biology Aged 80 and over Drug Implants Multimodal imaging 0303 health sciences business.industry General Medicine Middle Aged Visual symptoms Surgery Vitreous Body Ophthalmology Eye Foreign Bodies Intravitreal Injections 030221 ophthalmology & optometry Female Implant business Complication medicine.drug |
| Zdroj: | Retina |
| ISSN: | 0275-004X |
| Popis: | Purpose To describe the retention of large, tubular, nondissolving foreign bodies because of a complication of the intravitreal dexamethasone implant (Ozurdex). Methods This is a single-center, retrospective chart review of patients who were found to have retained, nondissolvable tubular foreign bodies in the vitreous cavity for more than 6 months (the expected dissolution time of the implants) after Ozurdex injections. Ocular symptomatology and multimodal imaging were reviewed. Results Five patients had retained, nondissolvable tubular foreign bodies in the vitreous that persisted for months (mean 28.2 months, range 9-67 months) after intravitreal injection of Ozurdex. Two patients were symptomatic due to the foreign bodies and chose alternate local therapy, but none of the patients opted for surgical explantation. Conclusion Persistent, nondissolving, tubular foreign bodies can be seen in the vitreous cavity for years after injection of the Ozurdex implant. Clinicians should be aware of this complication that has the potential to cause visual symptoms and ocular morbidity. |
| Databáze: | OpenAIRE |
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