Sexual selection and inbreeding: two efficient ways to limit the accumulation of deleterious mutations: A preprint peer-reviewed and recommended by Peer Community in Evolutionary Biology https://doi.org/10.24072/pci.evolbiol.10005

Autor: Adeline Segard, Elsa Noël, Violette Sarda, Elise Fruitet, Dennyss Lelaurin, Nicolás Bonel, Philippe Jarne, Patrice David
Přispěvatelé: Centre d’Ecologie Fonctionnelle et Evolutive (CEFE), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut National de la Recherche Agronomique (INRA)-Université Paul-Valéry - Montpellier 3 (UPVM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut de Recherche pour le Développement (IRD [France-Sud]), Max Planck Institute for Chemical Ecology, Max-Planck-Gesellschaft, Universidad Nacional del Sur [Argentina] (UNS), Université Paul-Valéry - Montpellier 3 (UM3)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-École pratique des hautes études (EPHE)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Noël, Elsa, French Agence Nationale de la Recherche' : AFFAIRS ANR-12-ADAP-005, ESHAP ANR-12-BSV7-0015, CNRS, CONICET, Université Paul-Valéry - Montpellier 3 (UPVM)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro)
Jazyk: angličtina
Rok vydání: 2018
Předmět:
0106 biological sciences
0301 basic medicine
Letter
Biología
01 natural sciences
purl.org/becyt/ford/1 [https]
hermaphrodite
snail
Inbreeding depression
mutation load
MUTATION LOAD
ComputingMilieux_MISCELLANEOUS
Genetics
0303 health sciences
Experimental evolution
Vegetal Biology
SNAIL
[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]
EXPERIMENTAL EVOLUTION
genetic load
Genetic load
Sexual selection
HERMAPHRODITE
Inbreeding
CIENCIAS NATURALES Y EXACTAS
Genetic purging
SELFING
Biology
purging
selfing
010603 evolutionary biology
Ciencias Biológicas
03 medical and health sciences
mating system
Letters
purl.org/becyt/ford/1.6 [https]
Ecology
Evolution
Behavior and Systematics
Selection (genetic algorithm)
030304 developmental biology
Reproductive success
Selfing
PURGING
Mating system
030104 developmental biology
[SDE.BE]Environmental Sciences/Biodiversity and Ecology
Biologie végétale
inbreeding depression
Zdroj: Evolution Letters 1 (3), 80-92. (2019)
Evolution Letters
Evolution Letters, Wiley Open Access 2019, 3 (1), pp.80-92. ⟨10.1002/evl3.93⟩
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Evolution Letters, 2019, 3 (1), pp.80-92. ⟨10.1002/evl3.93⟩
ISSN: 2056-3744
DOI: 10.1002/evl3.93⟩
Popis: Theory and empirical data showed that two processes can boost selection against deleterious mutations, thus facilitating the purging of the mutation load: inbreeding, by exposing recessive deleterious alleles to selection in homozygous form, and sexual selection, by enhancing the relative reproductive success of males with small mutation loads. These processes tend to be mutually exclusive because sexual selection is reduced under mating systems that promote inbreeding, such as self‐fertilization in hermaphrodites. We estimated the relative efficiency of inbreeding and sexual selection at purging the genetic load, using 50 generations of experimental evolution, in a hermaphroditic snail (Physa acuta). To this end, we generated lines that were exposed to various intensities of inbreeding, sexual selection (on the male function), and nonsexual selection (on the female function). We measured how these regimes affected the mutation load, quantified through the survival of outcrossed and selfed juveniles. We found that juvenile survival strongly decreased in outbred lines with reduced male selection, but not when female selection was relaxed, showing that male‐specific sexual selection does purge deleterious mutations. However, in lines exposed to inbreeding, where sexual selection was also relaxed, survival did not decrease, and even increased for self‐fertilized juveniles, showing that purging through inbreeding can compensate for the absence of sexual selection. Our results point to the further question of whether a mixed strategy combining the advantages of both mechanisms of genetic purging could be evolutionary stable. Fil: Noël, Elsa. Institut National de la Recherche Agronomique; Francia. Centre National de la Recherche Scientifique; Francia Fil: Fruitet, Elise. University of Amsterdam; Países Bajos. Max Planck Institute for Chemical Ecology; Alemania. Centre National de la Recherche Scientifique; Francia Fil: Lelaurin, Dennyss. Centre National de la Recherche Scientifique; Francia Fil: Bonel, Nicolás. Universidad Nacional del Sur; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centre National de la Recherche Scientifique; Francia Fil: Ségard, Adeline. Centre National de la Recherche Scientifique; Francia Fil: Sarda, Violette. Centre National de la Recherche Scientifique; Francia Fil: Jarne, Philippe. Centre National de la Recherche Scientifique; Francia Fil: David, Patrice. Centre National de la Recherche Scientifique; Francia
Databáze: OpenAIRE
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