An Experimental Study on Rapid Localization of the Atrioventricular Node During Open-Heart Surgery
| Autor: | Ke Chen, Libo Jin, Yangyang Li, Hao Wu, Qihong Huang, Shaohui Song, Chunhui Xiao, Yingjie Yang, Minghua Zhu, Guirong Lu |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Beating heart Swine law.invention Electrocardiography Postoperative Complications law Cardiopulmonary bypass medicine Animals cardiovascular diseases Cardiac Surgical Procedures Atrioventricular Block business.industry General Medicine Gold standard (test) Compression (physics) medicine.disease Atrioventricular node Surgery Disease Models Animal medicine.anatomical_structure Atrioventricular Node cardiovascular system Diagnostic odds ratio Swine Miniature Node (circuits) Cardiology and Cardiovascular Medicine business Atrioventricular block |
| Zdroj: | The Heart Surgery Forum. 23:E725-E730 |
| ISSN: | 1522-6662 1098-3511 |
| Popis: | Background: To verify the validity and feasibility of using a mechanical compression method to locate the atrioventricular node in open-heart surgery. Methods: Ten healthy miniature pigs were used to establish an animal model of the beating heart under cardiopulmonary bypass. During the operation, the atrioventricular node and its surrounding areas were stimulated by mechanical compression (mechanical compression method), and the occurrence of complete atrioventricular block was judged by real-time electrocardiograph monitoring and direct observation of the heart rhythm to identify the position of the atrioventricular node. The final localization of the atrioventricular node was determined using the iodine staining method, and the results were used as the "gold standard" to test the effectiveness and feasibility of the mechanical compression method for locating the atrioventricular node. Results: With the beating heart model, complete atrioventricular block occurred after mechanical compression of the "atrioventricular node" area in 10 pigs. Nine pigs regained normal conduction immediately after the compression was released, and one pig failed to recover. No atrioventricular block or other arrhythmias occurred after mechanical compression of the "non-atrioventricular node" area. The sensitivity of the method was 86.6%, specificity was 100.0%, misdiagnosis rate was 0.0%, missed diagnosis rate was 13.4%, positive predictive value was 100.0%, negative predictive value was 97.9%, positive likelihood ratios were +∞, negative likelihood ratios were 13.4%, accuracy was 98.1%, and diagnostic odds ratio was +∞. Conclusion: This study innovatively proposes the application of the mechanical compression method to locate the atrioventricular node during operation and preliminarily proves that this method is effective and feasible through animal experiments. |
| Databáze: | OpenAIRE |
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