ELIMINATION OF PROTEIN A-IgG COMPLEXES FROM THE BLOOD CIRCULATION IN RABBITS: ROLE OF SPLEEN AND LIVER
| Autor: | G. StÅlenheim, A. Bill, R. HÄllgren |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
Pathology medicine.medical_specialty medicine.medical_treatment Staphylococcal protein Spleen Antigen-Antibody Complex Iodine Radioisotopes Immune system Phagocytosis In vivo medicine Animals Tissue Distribution Serum Albumin Radio-Iodinated Staphylococcal Protein A Saline Isolated liver biology General Medicine Molecular biology medicine.anatomical_structure Liver Immunoglobulin G Blood circulation biology.protein Female Rabbits Protein A |
| Zdroj: | Acta Pathologica Microbiologica Scandinavica Section C Immunology. :435-440 |
| ISSN: | 0304-1328 |
| Popis: | We studied the elimination from rabbit circulation of soluble immune complexes made with staphylococcal protein A and rabbit IgG. In in vivo experiments the complexes were cleared from the circulation by the liver and spleen. In the saline perfused isolated liver there was rapid uptake of protein A-IgG complexes which indicated that the elimination of these complexes by fixed tissue macrophages may occur independent of complement components. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|