Vasoactive Agent Use in Septic Shock: Beyond First‐Line Recommendations
| Autor: | Ishaq Lat, Seth R. Bauer, Gretchen Sacha |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty First line 030106 microbiology Hemodynamics 030204 cardiovascular system & hematology Sepsis Norepinephrine (medication) Norepinephrine 03 medical and health sciences 0302 clinical medicine Refractory medicine Humans Vasoconstrictor Agents Pharmacology (medical) Intensive care medicine Septic shock business.industry medicine.disease Shock Septic Angiotensin II Shock (circulatory) medicine.symptom business medicine.drug |
| Zdroj: | Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 39:369-381 |
| ISSN: | 1875-9114 0277-0008 |
| Popis: | Septic shock is a life-threatening disorder associated with high mortality rates requiring rapid identification and intervention. Vasoactive agents are often required to maintain goal hemodynamics and preserve tissue perfusion. However, guidance regarding the proper administration of adjunct agents for the management of septic shock is limited in patients who are refractory to norepinephrine. This review summarizes vasopressor agents and describes the nuanced application of these agents in patients with septic shock, specifically focusing on clinical scenarios with limited guidance including patients who are nonresponsive to first-line agents and individuals with mixed shock states, tachyarrhythmias, obesity, valvular abnormalities, or other comorbid conditions. |
| Databáze: | OpenAIRE |
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