Synthesis, functionalization and properties of uniform europium-doped sodium lanthanum tungstate and molybdate (NaLa(XO4)2, X = Mo,W) probes for luminescent and X-ray computed tomography bioimaging
| Autor: | Ariadna Corral, Nuria O. Núñez, María Moros, Gabriel Lozano, Jesús M. de la Fuente, Manuel Ocaña, Mariano Laguna, Ana I. Becerro, Marcin Balcerzyk |
|---|---|
| Přispěvatelé: | Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), European Research Council, European Commission, Gobierno de Aragón, Consejo Superior de Investigaciones Científicas (España), Siemens Healthcare, Ministerio de Economía y Competitividad (España) |
| Rok vydání: | 2019 |
| Předmět: |
Luminescence
Materials science FOS: Physical sciences chemistry.chemical_element Applied Physics (physics.app-ph) 02 engineering and technology Molybdate 010402 general chemistry 01 natural sciences Biomaterials chemistry.chemical_compound Colloid and Surface Chemistry Europium Tungstate Lanthanum Carboxylate Functionalization NaLa(WO4)2 X-ray computed tomography Condensed Matter - Materials Science Polyacrylic acid Materials Science (cond-mat.mtrl-sci) Physics - Applied Physics 021001 nanoscience & nanotechnology 0104 chemical sciences 3. Good health Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry Nanoparticles 0210 nano-technology NaLa(MoO4)2 Ethylene glycol Nuclear chemistry |
| Zdroj: | Journal of Colloid and Interface Science Digital.CSIC. Repositorio Institucional del CSIC instname |
| ISSN: | 0021-9797 |
| Popis: | A one-pot simple procedure for the synthesis of uniform, ellipsoidal Eu3+-doped sodium lanthanum tungstate and molybdate (NaLa(XO4)2, X = W, Mo) nanophosphors, functionalized with carboxylate groups, is described. The method is based on a homogeneous precipitation process at 120 °C from appropriate Na+, Ln3+ and tungstate or molybdate precursors dissolved in ethylene glycol/water mixtures containing polyacrylic acid. A comparative study of the luminescent properties of both luminescent materials as a function of the Eu3+ doping level has been performed to find the optimum nanophosphor, whose efficiency as X-ray computed tomography contrast agent is also evaluated and compared with that of a commercial probe. Finally, the cell viability and colloidal stability in physiological pH medium of the optimum samples have also been studied to assess their suitability for biomedical applications. This work has been supported by the Spanish Ministry of Science, Innovation and Universities, Spain (RTI2018-094426-B-I00), the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (NANOPHOM, grant agreement no. 715832), DGA and Fondos Feder, Aragón, Spain (Bionanosurf E15_17R) and CSIC, Spain (PIC2016FR1). This work was also supported in part by Siemens Healthcare S.L.U., Spain MM thanks MINECO, Spain for Juan de la Cierva Fellowship. |
| Databáze: | OpenAIRE |
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