Etiology and Medical Management of Pediatric Intestinal Failure
| Autor: | Valeria C. Cohran, Ethan A. Mezoff, Conrad R. Cole |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Short Bowel Syndrome medicine.medical_specialty Catheterization Central Venous Parenteral Nutrition medicine.medical_treatment Enteral administration 03 medical and health sciences Liver disease 0302 clinical medicine Enteral Nutrition Gastrointestinal Agents Intestinal failure Medicine Humans Endoscopy Digestive System Micronutrients Intensive care medicine Child Patient Care Team business.industry Liver Diseases Gastroenterology Avitaminosis Bowel resection medicine.disease Short bowel syndrome Adaptation Physiological 030104 developmental biology Parenteral nutrition Multicenter study Etiology 030211 gastroenterology & hepatology business |
| Zdroj: | Gastroenterology clinics of North America. 48(4) |
| ISSN: | 1558-1942 |
| Popis: | Pediatric intestinal failure occurs when gut function is insufficient to meet the growing child's hydration and nutrition needs. After massive bowel resection, the remnant bowel adapts to lost absorptive and digestive capacity through incompletely defined mechanisms newly targeted for pharmacologic augmentation. Management seeks to achieve enteral autonomy and mitigate the development of comorbid disease. Care has improved, most notably related to reductions in blood stream infection and liver disease. The future likely holds expansion of pharmacologic adaptation augmentation, refinement of intestinal tissue engineering techniques, and the development of a learning health network for efficient multicenter study and care improvement. |
| Databáze: | OpenAIRE |
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