Cocreated internet-based stepped care for individuals with cancer and concurrent symptoms of anxiety and depression : Results from the U-CARE AdultCan randomized controlled trial

Autor: Helena Igelström, Birgitta Johansson, Louise von Essen, Anna Hauffman, Susanne Mattsson, Marina Forslund, Peter Nygren, Sven Alfonsson, Anna Bill-Axelson, Leif Bergkvist
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
medicine.medical_treatment
Anxiety
Hospital Anxiety and Depression Scale
law.invention
Stress Disorders
Post-Traumatic

0302 clinical medicine
Randomized controlled trial
Quality of life
law
Neoplasms
Medicine
030212 general & internal medicine
technology-based interventions
Depression (differential diagnoses)
Depression
Middle Aged
anxiety
Telemedicine
Cognitive behavioral therapy
Psychiatry and Mental health
Treatment Outcome
030220 oncology & carcinogenesis
Papers
depression
oncology
Female
medicine.symptom
Paper
Adult
medicine.medical_specialty
Randomization
Experimental and Cognitive Psychology
Nursing
psychosocial intervention
technology‐based interventions
03 medical and health sciences
Psychoeducation
Humans
cancer
Internet
Cancer och onkologi
Cognitive Behavioral Therapy
business.industry
Omvårdnad
psycho‐oncology
Cancer and Oncology
randomized controlled trial
Physical therapy
Quality of Life
psycho-oncology
eHealth
Self Report
internet
business
Zdroj: Psycho-Oncology
Popis: Objective The aim was to evaluate the effects of cocreated internet-based stepped care (iCAN-DO) on anxiety, depression, posttraumatic stress, and health-related quality of life (HRQoL) in individuals with cancer and self-reported anxiety and/or depression symptoms, compared with standard care. Methods Clinically recruited individuals with breast, colorectal, or prostate cancer underwent online screening with the Hospital Anxiety and Depression Scale (HADS). Those with anxiety and/or depression symptoms (>7 on any of the HADS subscales) were randomized to iCAN-DO or standard care. iCAN-DO comprised psychoeducation and self-care strategies (step 1) and internet-based cognitive behavioral therapy (iCBT, step 2). Data were collected before randomization and at 1, 4, 7, and 10 months and analyzed with intention-to-treat regression analysis and randomization tests. Results Online screening identified 245 (27%) of 909 individuals who reported anxiety and/or depression symptoms. They were randomized to iCAN-DO (n = 124) or standard care (n = 121). Of them 49% completed the 10-month assessment, and in the iCAN-DO group 85% accessed step 1 and 13% underwent iCBT. iCAN-DO decreased the levels of symptoms of depression (−0.54, 95% confidence interval: −1.08 to −0.01, P < .05) and the proportion of individuals with symptoms of depression (P < .01) at 10 months, compared with standard care, according to HADS. There were no significant effects on anxiety, posttraumatic stress, or HRQoL. Conclusion Internet-based stepped care improves symptoms of depression in individuals with cancer. Further studies are needed to gain knowledge on how to optimize and implement internet-based support in oncology care.
Databáze: OpenAIRE