Botulinum toxin: Non cosmetic and off-label dermatological uses
| Autor: | Noah Alghanemy, Dhafer Al-Qahtani, Ali S. Al-Ghamdi, Hanan Joharji, Hasan S. Al-Ghamdi |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
business.industry Toxin Hyperhidrosis Leiomyoma-related pain Raynaud Syndrome lcsh:RL1-803 medicine.disease_cause Off-label use Botulinum toxin Dermatology Lichen simplex chronicus Norepinephrine (medication) lcsh:Dermatology Hailey-Hailey Medicine Neurotoxin Clostridium botulinum Post-herpetic Neuralgia medicine.symptom business Acetylcholine medicine.drug |
| Zdroj: | Journal of Dermatology and Dermatologic Surgery, Vol 19, Iss 1, Pp 1-8 (2015) |
| ISSN: | 2352-2410 |
| DOI: | 10.1016/j.jdds.2014.06.002 |
| Popis: | Botulinum toxin (BT-A) is a neurotoxin which is produced by the Gram-positive anaerobic bacterium Clostridium botulinum . The efficacy of Botulinum toxin in treating hyperhidrosis and the glabellar lines is well known and FDA approved. Because BT-A inhibits the release of acetylcholine and many other neurotransmitters such as norepinephrine and substance P at the level of nerve ending, this toxin has been used to treat a lot of dermatological disorders which are thought to be triggered by these neurotransmitters. In this article we are discussing the medical off-label uses of BT-A in dermatology. |
| Databáze: | OpenAIRE |
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