Adoption of Pharmacogenomic Testing by US Physicians: Results of a Nationwide Survey
| Autor: | Felix W. Frueh, Ronald E. Aubert, Barnabie C Agatep, Robert R. Verbrugge, A Patel, K A Johansen Taber, C. Sanders, Mona Khalid, Edward J. Stanek, Robert S. Epstein |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Gerontology Health Knowledge Attitudes Practice medicine.medical_specialty Multivariate analysis Attitude of Health Personnel Population MEDLINE Pharmacogenomic Testing Logistic regression Young Adult Surveys and Questionnaires medicine Humans Pharmacology (medical) Genetic Testing Practice Patterns Physicians' Young adult education Aged Pharmacology education.field_of_study business.industry Data Collection Genetic Variation Middle Aged United States Test (assessment) Cross-Sectional Studies Logistic Models Pharmacogenetics Family medicine Multivariate Analysis Female business Pharmacogenetic Test |
| Zdroj: | Clinical Pharmacology & Therapeutics. 91:450-458 |
| ISSN: | 1532-6535 0009-9236 |
| Popis: | To develop a benchmark measure of US physicians' level of knowledge and extent of use of pharmacogenomic testing, we conducted an anonymous, cross-sectional, fax-based, national survey. Of 397,832 physicians receiving the survey questionnaire, 10,303 (3%) completed and returned it; the respondents were representative of the overall US physician population. The factors associated with the decision to test were evaluated using χ(2) and multivariate logistic regression. Overall, 97.6% of responding physicians agreed that genetic variations may influence drug response, but only 10.3% felt adequately informed about pharmacogenomic testing. Only 12.9% of physicians had ordered a test in the previous 6 months, and 26.4% anticipated ordering a test in the next 6 months. Early and future adopters of testing were more likely to have received training in pharmacogenomics, but only 29.0% of physicians overall had received any education in the field. Our findings highlight the need for more effective physician education on the clinical value, availability, and interpretation of pharmacogenomic tests. |
| Databáze: | OpenAIRE |
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