Evidence-based treatment for advanced germ cell tumor of the testis with a case illustration
| Autor: | Han-Ting Liu, Chung-King Lin |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Oncology
Male medicine.medical_specialty Adolescent literature review Testicular Germ Cell Tumor Bleomycin Embryonal carcinoma chemistry.chemical_compound evidence-based management Testicular Neoplasms Internal medicine case illustration Antineoplastic Combined Chemotherapy Protocols medicine Humans Young adult Etoposide Neoplasm Staging Gynecology Medicine(all) lcsh:R5-920 business.industry Cancer General Medicine Neoplasms Germ Cell and Embryonal medicine.disease medicine.anatomical_structure chemistry Evidence-Based Practice testicular germ cell tumor Germ cell tumors Cisplatin business lcsh:Medicine (General) Tomography X-Ray Computed Germ cell medicine.drug Follow-Up Studies |
| Zdroj: | Journal of the Chinese Medical Association, Vol 73, Iss 7, Pp 343-352 (2010) |
| ISSN: | 1728-7731 |
| Popis: | Testicular germ cell tumor is rare in the Asian population. Nevertheless, it is a prototypic cancer of young adults because it can be highly malignant but is also highly curable, even at an advanced stage. We present a case with far-advanced embryonal carcinoma, treated with bleomycin, etoposide and platinum (BEP) x 4 cycles. This case has shown very good results from the treatment. This is the standard therapy for poor- and intermediate-risk patients with germ cell tumors in the advanced stage, supported by current evidence-based literature. BEP x 3 cycles or EP x 4 cycles is the standard therapy for good-risk patients with advanced germ cell tumors. Using these treatments, we can achieve durable remissions of approximately 90%, 75%, and 45% in good-, intermediate-, and poor-risk patients, respectively. However, the physical and psychological long-term outcomes should be carefully monitored. |
| Databáze: | OpenAIRE |
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