Fine-needle aspiration cytology of metastatic transitional cell carcinoma
| Autor: | Thasneem Amir, Pranab Dey, Aisha Al Jussar, Sanjay Jogai |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Male
medicine.medical_specialty Pathology Skin Neoplasms Histology Cytodiagnosis Biopsy Fine-Needle Pathology and Forensic Medicine Cytology Biopsy medicine Carcinoma Humans Neoplasm Metastasis Lymph node Aged Carcinoma Transitional Cell Metastatic Transitional Cell Carcinoma Urinary bladder medicine.diagnostic_test business.industry General Medicine Middle Aged medicine.disease medicine.anatomical_structure Transitional cell carcinoma Urinary Bladder Neoplasms Histopathology Lymph Nodes business |
| Zdroj: | Diagnostic Cytopathology. 32:226-228 |
| ISSN: | 1097-0339 8755-1039 |
| DOI: | 10.1002/dc.20199 |
| Popis: | In this article we described the fine-needle aspiration cytology (FNAC) of five cases of metastatic transitional cell carcinoma (TCC). There were four cases of metastatic lymph nodes and one case of metastatic skin lesion. All of the TCC cases were primarily in the urinary bladder and were high grade on histopathology (grade 3). Three cases showed bladder muscle involvement and two cases showed superficial TCC at the time of primary diagnosis. FNAC smears showed abundant cellularity. The cells were present in discrete and small syncytial clusters. Nuclear position of the cell was central to eccentric. Many cells showed prominent nucleoli. Cercariform cells (CCs) were noted in four cases. These cells are malignant cells with a nucleated globular body and a unipolar nontapering cytoplasmic process. Two cases showed intranuclear inclusions. Prominent cytoplasmic vacuoles were noted in three cases. In addition, cell cannibalism and attempted pearl formations were noted in two cases.In conclusion, clinical history along with the certain cytological features such as the presence of CCs, cells with eccentric nuclei, and intranuclear inclusions are helpful to diagnose metastatic TCC on FNAC material. |
| Databáze: | OpenAIRE |
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