Effectiveness of practices to reduce blood sample hemolysis in EDs: A laboratory medicine best practices systematic review and meta-analysis
| Autor: | Diana Mass, Colleen S. Shaw, James H. Derzon, Paul Epner, Nicholas J. Heyer, Edward Liebow, Linda D. Winges, Julie Gayken, Susan R. Snyder, James H. Nichols, Dennis J. Ernst |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Program evaluation
medicine.medical_specialty Evidence-based practice Catheters Databases Factual Best practice Clinical Biochemistry Medical laboratory Sample (statistics) Hemolysis Article Medical Laboratory Personnel medicine Odds Ratio Humans Intensive care medicine Blood Specimen Collection business.industry Syringes General Medicine Emergency department medicine.disease humanities Meta-analysis Evidence-Based Practice Practice Guidelines as Topic business Emergency Service Hospital Program Evaluation |
| Popis: | To complete a systematic review of emergency department (ED) practices for reducing hemolysis in blood samples sent to the clinical laboratory for testing.A total of 16 studies met the review inclusion criteria (12 published and 4 unpublished). All 11 studies comparing new straight needle venipuncture with IV starts found a reduction in hemolysis rates, [average risk ratio of 0.16 (95% CI=0.11-0.24)]. Four studies on the effect of venipuncture location showed reduced hemolysis rates for the antecubital site [average risk ratio of 0.45 (95% CI=0.35-0.57].Use of new straight needle venipuncture instead of IV starts is effective at reducing hemolysis rates in EDs, and is recommended as an evidence-based best practice. The overall strength of evidence rating is high and the effect size is substantial. Unpublished studies made an important contribution to the body of evidence. When IV starts must be used, observed rates of hemolysis may be substantially reduced by placing the IV at the antecubital site. |
| Databáze: | OpenAIRE |
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