Detection of Asymptomatic Cardiac Metastasis and Successful Salvage Chemotherapy Comprising a Prednisone, Etoposide, Procarbazine, and Cyclophosphamide Regimen in an Elderly Japanese Patient Suffering from a Delayed Recurrence of Diffuse Large B-Cell Lymphoma
| Autor: | Atsushi Tashiro, Hiroshi Kato, Keita Tagami, Tatsuya Komaru, Hiroshi Nakura, Ken-ya Saji, Kenichi Ishizawa, Shigeru Tanda, Muneo Tanida |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Oncology
medicine.medical_specialty Vincristine Cyclophosphamide PET/CT Prednisone etoposide procarbazine and cyclophosphamide regimen Procarbazine lcsh:RC254-282 Published: January 2012 Prednisone Recurrence Internal medicine hemic and lymphatic diseases Medicine Cardiac MRI Cardiac metastasis Prednisone etoposide procarbazine and cyclophosphamide regimen Etoposide Cardiacmetastasis business.industry Malignant lymphoma Diffuse large B-cell lymphoma medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Regimen Rituximab Radiology Salvage chemotherapy business medicine.drug |
| Zdroj: | Case Reports in Oncology, Vol 5, Iss 1, Pp 62-68 (2012) Case Reports in Oncology |
| ISSN: | 1662-6575 |
| Popis: | We report a case of facial diffuse large B-cell lymphoma (DLBCL) associated with recurrent metastasis in the heart and other sites in a 76-year-old Japanese woman. Initially, she developed DLBCL in her left upper eyelid that spread into the left orbit (Ann Arbor classification stage I). The lesion went into clinical regression after 4 cycles of rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy followed by radiotherapy. More than 3 years later, the lymphoma recurred in her facial skin, together with metastases in the mediastinal lymph nodes and the heart; the tumor in the heart was successfully detected by PET/CT and cardiac MRI. To treat the recurrent lesions, we performed a salvage chemotherapy regimen comprising prednisone, etoposide, procarbazine, and cyclophosphamide, which successfully induced tumor regression. |
| Databáze: | OpenAIRE |
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