Extracellular electron transfer systems fuel cellulose oxidative degradation
| Autor: | Erik Breslmayr, Marita Preims, Vincent G. H. Eijsink, Karolina Ludwicka, Daniel Kracher, Alfons K. G. Felice, Dietmar Haltrich, Stefan Scheiblbrandner, Roland Ludwig |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Cellobiose dehydrogenase 030106 microbiology Electron donor Oxidative phosphorylation Biology Polysaccharide Lignin Mixed Function Oxygenases Electron Transport Fungal Proteins 03 medical and health sciences chemistry.chemical_compound Electron transfer Extracellular Cellulose chemistry.chemical_classification Multidisciplinary Fungi Monooxygenase 030104 developmental biology Biochemistry chemistry Biocatalysis Genome Fungal Oxidation-Reduction |
| Zdroj: | Science (New York, N.Y.). 352(6289) |
| ISSN: | 1095-9203 |
| Popis: | The fuel for fungal enzymes Many microorganisms have specialized enzymes to target and break down plant biomass. In fungi, these enzymes, called lytic polysaccharide monooxygenases (LPMOs), partner with electron transfer partners to oxidatively cleave the polysaccharide backbone of lignocellulosic polymers. Kracher et al. examined several potential extracellular electron transfer partners for LPMO, including other enzymes and small redoxactive metabolites (see the Perspective by Martínez). All three were able to donate electrons to the single-copper active site. Such versatility helps these fungi adapt to a range of redox conditions and potentially use other extracellular electron donors to fuel biomass degradation. Science , this issue p. 1098 ; see also p. 1050 |
| Databáze: | OpenAIRE |
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