Individual resistance to cerebral ischemia and negative effect of emotional stress on the course of this disorder
| Autor: | E. V. Koplik, I. V. Gannushkina, G. V. Pirogova, I. L. Konorova, A. L. Antelava |
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| Rok vydání: | 2004 |
| Předmět: |
Male
medicine.medical_specialty Ischemia Collateral Circulation General Biochemistry Genetics and Molecular Biology Brain Ischemia Immobilization Internal medicine medicine.artery Occlusion medicine Animals Common carotid artery Cerebral perfusion pressure Rats Wistar business.industry Electroencephalography General Medicine Emotional stress medicine.disease Rats Collateral flow Cerebral blood flow Anesthesia Cerebrovascular Circulation Cardiology Seasons business Stress Psychological |
| Zdroj: | Bulletin of experimental biology and medicine. 137(2) |
| ISSN: | 0007-4888 |
| Popis: | The ratio of low-activity and high-activity rats differed in autumn, winter, and spring litters. Initially more intensive cerebral blood flow in low-active rats and its more pronounced decrease after common carotid artery occlusion determined their higher sensitivity to cerebral ischemia (compared to high-activity animals). After 18-h immobilization stress cerebral blood flow decreased by 10-15%, which abolished the difference in the individual resistance to cerebral ischemia. Independently on emotional resistance, cerebral ischemia was not accompanied by the development of collateral blood flow in the acute period and caused death of 90% rats. |
| Databáze: | OpenAIRE |
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