Date Fruits-Assisted Synthesis and Biocompatibility Assessment of Nickel Oxide Nanoparticles Anchored onto Graphene Sheets for Biomedical Applications
| Autor: | Vaiyapuri Subbarayan Periasamy, Jegan Athinarayanan, Khalid A. Alatiah, Ali A. Alshatwi |
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| Rok vydání: | 2016 |
| Předmět: |
Materials science
Biocompatibility Cell Survival Oxide Metal Nanoparticles Nanoparticle Bioengineering Nanotechnology 02 engineering and technology 010402 general chemistry 01 natural sciences Applied Microbiology and Biotechnology Biochemistry law.invention chemistry.chemical_compound Coated Materials Biocompatible Nickel law Materials Testing Humans Fourier transform infrared spectroscopy Molecular Biology Plant Extracts Graphene Nickel oxide Non-blocking I/O Phoeniceae Mesenchymal Stem Cells General Medicine 021001 nanoscience & nanotechnology 0104 chemical sciences Absorption Physicochemical chemistry Surface modification Graphite 0210 nano-technology Biotechnology |
| Zdroj: | Applied Biochemistry and Biotechnology. 181:725-734 |
| ISSN: | 1559-0291 0273-2289 |
| DOI: | 10.1007/s12010-016-2244-z |
| Popis: | Nanographene- and graphene-based nanohybrids have garnered attention in the biomedical community owing to their biocompatibility, excellent aqueous processability, ease of cellular uptake, facile surface functionalization, and thermal and electrical conductivities. NiO nanoparticle-graphene nanohybrid (G-NiO) was synthesized by first depositing Ni(OH)2 onto the surface of graphene oxide (GO) sheets. The Ni(OH)2-GO hybrids were then reduced to G-NiO using date palm syrup at 85 °C. The prepared G-NiO nanohybrids were characterized by X-ray diffraction (XRD), field-emission scanning electron microscopy (FESEM), Fourier transform infrared spectroscopy, and energy-dispersive X-ray spectroscopy (EDX). The NiO nanoparticles, with a diameter of approximately 20-30 nm, were uniformly dispersed over the surface of the graphene sheets. The G-NiO hybrids exhibit biocompatibility in human mesenchymal stem cells (hMSCs) up to 100 μg/mL. The nanohybrids do not cause any significant changes in cellular and nuclear morphologies in hMSCs. The as-synthesized nanohybrids show excellent biocompatibility and could be a promising material for biomedical applications. |
| Databáze: | OpenAIRE |
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