The Prognostic Value of Prehospital Blood Lactate Levels to Predict Early Mortality in Acute Cardiovascular Disease
Autor: | José Luis Martín Conty, Francisco Martín-Rodríguez, Carlos Del Pozo Vegas, Miguel A. Castro Villamor, Agustín Mayo-Iscar, María Del Pilar Delgado Benito, Irene Sánchez-Soberón, Vicente Martinez, Gemma Pastor Baez, Carmen M Martínez Caballero, Raúl López-Izquierdo |
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Rok vydání: | 2020 |
Předmět: |
Male
Emergency Medical Services medicine.medical_specialty 030204 cardiovascular system & hematology Critical Care and Intensive Care Medicine Chest pain 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Internal medicine Emergency medical services Humans Multicenter Studies as Topic Medicine Lactic Acid Prospective Studies Prospective cohort study Aged Aged 80 and over business.industry Area under the curve 030208 emergency & critical care medicine Emergency department Middle Aged Prognosis Confidence interval Advanced life support ROC Curve Cardiovascular Diseases Predictive value of tests Acute Disease Emergency Medicine Female medicine.symptom business |
Zdroj: | Shock. 53:164-170 |
ISSN: | 1540-0514 1073-2322 |
Popis: | INTRODUCTION The knowledge of the prognostic value of prehospital lactate (PLA) is limited. Our objective was to evaluate the predictive capacity of PLA to predict early mortality (within 48 h) from the index event in acute cardiovascular disease (ACVD). METHODS Prospective, longitudinal, multicenter, observational study in patients, attended by advanced life support units, transferred to the emergency department of their reference hospital and diagnosed with ACVD. We collected demographic, physiological, clinical, analytical variables, main cardiological diagnosis, and data on hospital admission and early mortality. The main outcome variable was mortality from any cause within 2 days. RESULTS Between March 1, 2018 and January 31, 2019, a total of 492 patients were included in our study. Early mortality after the index event within the first 48 h affected 27 patients (5.5%). The most frequent cause of care demand was chest pain with 223 cases (45.3%). The predictive power of PLA to discriminate mortality at 2 days obtained an area under the curve of 0.911 (95% confidence interval [CI]: 0.83-0.98, P |
Databáze: | OpenAIRE |
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