Stability of analytes related to clinical chemistry and bone metabolism in blood specimens after delayed processing
| Autor: | Scott M. Smith, PL Gillman, Shanna Rodgers, Sara R. Zwart, Ann Rogers, Megan Wolf, Kristen Hitchcox, Karen L. Ericson |
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| Rok vydání: | 2009 |
| Předmět: |
Analyte
medicine.medical_specialty Time Factors Homocysteine Osteocalcin Clinical Biochemistry Parathyroid hormone Centrifugation Bone and Bones Specimen Handling Bone remodeling chemistry.chemical_compound Phlebotomy Internal medicine medicine Humans Pyridoxal biology General Medicine Endocrinology chemistry Parathyroid Hormone Chemistry Clinical Pyridoxal Phosphate biology.protein |
| Zdroj: | Clinical Biochemistry. 42:907-910 |
| ISSN: | 0009-9120 |
| DOI: | 10.1016/j.clinbiochem.2009.02.010 |
| Popis: | Objectives We investigated the stability of 36 analytes related to clinical chemistry in a controlled storage study. Design and methods Blood was collected from 11 subjects and was maintained for 45 min, 2.5 h, 5 h, or 24 h after phlebotomy before centrifugation. Results Statistically significant changes were observed only for parathyroid hormone, osteocalcin, zinc, pyridoxal 5′-phosphate, and homocysteine. Conclusions These studies indicate that many analytes in clinical chemistry are stable for 24 h before centrifugation. |
| Databáze: | OpenAIRE |
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