The Lowest Prevalence of Cholelithiasis in the Americas - An Autopsy-based Study
Autor: | André Marangoni Asperti, Paulo Eduardo Ocke Reis, Marcio A. Diniz, Danilo Felipe Dias da Silva, Edinésio Carlos da Silva Júnior, Luiz Augusto Carneiro D'Albuquerque, Mariana Dourado Pinto, Wellington Andraus |
---|---|
Jazyk: | angličtina |
Předmět: |
Adult
Male medicine.medical_specialty Alcohol Drinking Cross-sectional study medicine.medical_treatment Population Gallbladder disease Autopsy Gallstones Statistics Nonparametric Body Mass Index 03 medical and health sciences 0302 clinical medicine Age Distribution Sex Factors Risk Factors Cholelithiasis Internal medicine medicine Prevalence Humans Prospective Studies Sex Distribution education Prospective cohort study Aged education.field_of_study lcsh:R5-920 business.industry Age Factors General Medicine Middle Aged Clinical Science medicine.disease Surgery Cross-Sectional Studies 030220 oncology & carcinogenesis Cholecystectomy Female Americas business lcsh:Medicine (General) Body mass index Brazil |
Zdroj: | Clinics, Vol 71, Iss 7, Pp 365-369 Clinics Clinics; v. 71 n. 7 (2016); 365-369 Clinics; Vol. 71 Núm. 7 (2016); 365-369 Clinics; Vol. 71 No. 7 (2016); 365-369 Universidade de São Paulo (USP) instacron:USP Clinics, Volume: 71, Issue: 7, Pages: 365-369, Published: JUL 2016 |
ISSN: | 1980-5322 1807-5932 |
Popis: | OBJECTIVES: This study used autopsy to evaluate the prevalence of cholelithiasis and its associated risk factors in a population of healthy, young subjects who suffered a violent or natural death. METHODS: This study is a prospective evaluation of autopsies of 446 individuals from 2011 to 2013 in Brazil. Of that sample, 330 (74%) subjects died from violent deaths and 116 (26%) died naturally. The presence of biliary calculi, previous cholecystectomy, gender, age, ethnicity, body mass index (BMI) and alcohol use were evaluated. RESULTS: In the natural death group, 6.9% (95% CI 3.39 to 13.28) (3.08% of the male subjects and 11.76% of the female subjects) exhibited evidence of gallbladder disease. In the violent death group, only 2.12% (95% CI 0.96 to 4.43) (2.17% of the male subjects and 1.85% of the female subjects) of the subjects exhibited evidence of gallbladder disease. Age was correlated with the prevalence of gallbladder disease, but BMI was correlated with only gallbladder disease in the natural death group. CONCLUSIONS: This population has the lowest prevalence of cholelithiasis in the Americas. Dietary habits, physical activity, ethnicity, alcohol consumption and genetic factors may be responsible for this low prevalence. |
Databáze: | OpenAIRE |
Externí odkaz: |