A Wireless Integrated Circuit for 100-Channel Charge-Balanced Neural Stimulation

Autor: David J. Warren, Gregory A. Clark, Noah M. Ledbetter, Reid R. Harrison, B.K. Thurgood
Rok vydání: 2009
Předmět:
Zdroj: IEEE Transactions on Biomedical Circuits and Systems. 3:405-414
ISSN: 1940-9990
1932-4545
Popis: The authors present the design of an integrated circuit for wireless neural stimulation, along with benchtop and in - vivo experimental results. The chip has the ability to drive 100 individual stimulation electrodes with constant-current pulses of varying amplitude, duration, interphasic delay, and repetition rate. The stimulation is performed by using a biphasic (cathodic and anodic) current source, injecting and retracting charge from the nervous system. Wireless communication and power are delivered over a 2.765-MHz inductive link. Only three off-chip components are needed to operate the stimulator: a 10-nF capacitor to aid in power-supply regulation, a small capacitor (< 100 pF) for tuning the coil to resonance, and a coil for power and command reception. The chip was fabricated in a commercially available 0.6- mum 2P3M BiCMOS process. The chip was able to activate motor fibers to produce muscle twitches via a Utah Slanted Electrode Array implanted in cat sciatic nerve, and to activate sensory fibers to recruit evoked potentials in somatosensory cortex.
Databáze: OpenAIRE