An easy stereospecific synthesis of 1-amino-2,5-anhydro-1-deoxy-D-mannitol and arylamino derivatives
| Autor: | Jacques Périé, Michele Willson, Laurent Azema, Samantha Claustre, Frédéric Bringaud, Rudi Baron |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Monosaccharide Transport Proteins
Stereochemistry Molecular Sequence Data Trypanosoma brucei brucei Deamination Trypanosoma brucei Biochemistry Reductive amination Analytical Chemistry chemistry.chemical_compound Stereospecificity Hexose Transporter parasitic diseases medicine Animals Mannitol Nitrous acid biology Chemistry Organic Chemistry General Medicine biology.organism_classification Kinetics Carbohydrate Sequence D-mannitol medicine.drug |
| Zdroj: | Carbohydrate research. 315(3-4) |
| ISSN: | 0008-6215 |
| Popis: | 1-Amino-2,5-anhydro-1-deoxy- d -mannitol and a series of arylamino derivatives were prepared by nitrous acid deamination of 2-amino-2-deoxy- d -glucose and subsequent reductive amination of the resulting 2,5-anhydro- d -mannose. Some of these compounds showed an enhanced affinity for the hexose transporter of Trypanosoma brucei as compared to d -fructose. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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