Impact of surgery associated with radiotherapy on the prognosis of breast cancer - Guinea Breast Cancer Cohort Study
| Autor: | Assiatou Barry, Abdoulaye Touré, Bangaly Traore, Ibrahima Camara, Moussa Koulibaly, M. Keita |
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| Rok vydání: | 2021 |
| Předmět: |
Cancer Research
medicine.medical_specialty Multivariate analysis medicine.medical_treatment Breast Neoplasms Overweight Cohort Studies Breast cancer medicine Humans Retrospective Studies Chemotherapy Proportional hazards model business.industry medicine.disease Prognosis Surgery Radiation therapy Oncology Female Guinea medicine.symptom Neoplasm Recurrence Local business Adjuvant Cohort study |
| Zdroj: | Cancer reports (Hoboken, N.J.). 5(9) |
| ISSN: | 2573-8348 |
| Popis: | BACKGROUND In a country where radiotherapy (RT) is not available, advocacy based on the relevance of surgery + adjuvant RT in locoregional control and survival is needed. AIM To evaluate the impact of surgery with RT on local control and survival compared to surgery alone in breast cancer (BC). METHODS AND RESULTS Between 2007 and 2016, 210 patients with BC were retrospectively reviewed, of which 90 patients underwent surgery with RT (group 1) and 120 patients' surgery (group 2). There were several treatment combinations, including surgery combined with neoadjuvant chemotherapy [ACT], RT, and ACT. The results showed 88 (41.9%) cases of relapse, including 31 (34.4%) (group 1) and 57 (47.5%) (group 2) (p = .046). Recurrence occurred after a mean time of 1.5 years in group 1 versus 0.66 years in group 2 (p = .006). The 5-year overall and BC-specific survivals were 49.5% and 62.5%, respectively. The 5-year survival was 60.0% (group 1) and 40.0% (group 2) (p |
| Databáze: | OpenAIRE |
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