Synthesis and insecticidal activity of benzoheterocyclic analogues of N'-benzoyl-N-(tert-butyl)benzohydrazide: Part 1. Design of benzoheterocyclic analogues
| Autor: | Toshiaki Yanai, Yoshihisa Tsukamoto, Yoshihiro Sawada, Yoshimi Yajima, Tetsuya Toya, Mikio Yanagi, Hidetoshi Shirakura, Seiichirou Kodama, Hiroyasu Sugizaki, Yasuhito Kato, Harumi Nakagawa, Shinji Yokoi, Tetsuo Watanabe, Akio Masui |
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| Rok vydání: | 2003 |
| Předmět: |
Indole test
Tebufenozide Insecticides Molecular Structure Hydrazine Spodoptera litura General Medicine Benzoxazole Biology Spodoptera biology.organism_classification Chemical synthesis Medicinal chemistry chemistry.chemical_compound Hydrazines Benzothiazole chemistry Heterocyclic Compounds Insect Science Drug Design Larva Botany Phenyl group Animals Agronomy and Crop Science |
| Zdroj: | Pest management science. 59(1) |
| ISSN: | 1526-498X |
| Popis: | The N'-benzoyl group of N-tert-butyl-N'-benzoyl-3,5-dimethylbenzohydrazide (1) was converted to a series of benzoheterocyclecarbonyl groups in order to investigate the potential usefulness of superimposing a hydrazine insecticide on 20-hydroxyecdysone. A series of analogues with benzodioxole, benzodioxane, benzodioxapine, indole, benzoxazole, benzoxazine or benzothiazole instead of the phenyl group of (1) were synthesized and tested for their insecticidal activity against the common cutworm (Spodoptera litura F). N-tert-Butyl-N'-(3,5-dimethylbenzoyl)-1,3-benzodioxole-5-carbohydrazide and N-tert-butyl-N'-(3,5-dimethylbenzoyl)-2,3-dihydro-1,4-benzodioxine-6-carbohydrazide showed high insecticidal activities, superior to that of (1) and equal to that of the commercial insecticide tebufenozide (RH-5992). |
| Databáze: | OpenAIRE |
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