Focal vitreomacular traction: a prospective study of the evolution to macular hole: the mathematical approach
| Autor: | A L Moustakas, M. I. Eleftheriadou, I Datseris, Panagiotis Theodossiadis, Petros Petrou, George Theodossiadis |
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| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty genetic structures medicine.medical_treatment Retinal perforation Tissue Adhesions Vitrectomy Endotamponade Vitreomacular traction Vitreous Detachment Retinal Diseases Prone Position medicine Humans Prospective Studies Prospective cohort study Macular hole Aged Fluorocarbons business.industry Middle Aged Models Theoretical Retinal Perforations medicine.disease eye diseases Surgery Ophthalmology Prone position surgical procedures operative Clinical Study Female sense organs business Tomography Optical Coherence |
| Zdroj: | Eye. 28:1452-1460 |
| ISSN: | 1476-5454 0950-222X |
| DOI: | 10.1038/eye.2014.223 |
| Popis: | PURPORSE: To determine the associated balance of forces of the vitreofoveal interface in focal vitreomacular traction evolving to full-thickness macular hole (FTMH) and to link/explain the observed changes in the context of mathematical and physics models.This is a multicenter, prospective, and observational case series conducted at the Vitreoretinal Department of three different referral centers. Fellow eyes of patients with unilateral idiopathic FTMH were included. Eighty-nine patients were included in the analysis. The fellow normal eye of the study patients was imaged with spectral-domain optical coherence tomography. The main outcome measure was the optical-coherence-tomography-defined characteristics of the vitreofoveal interface and their analysis with mathematical and physics models at the end of follow-up period.Of the included 89 patients (66 women and 23 men; mean age±SD, 68.5 years±9.8), 10 (11.2%) developed FTMH at the fellow eye at the end of the follow-up period. We observed two types of vitreofoveal attachment. A V-shaped (cord-like) configuration and a U-shaped configuration. The eyes with the V-shaped attachment demonstrated initial structural changes in the outer foveal layers and the eyes with the U-shaped attachment showed inner morphological changes.We hypothesize that the type (V- or U-shaped) of the vitreofoveal attachment may affect the type and location of the initial structural change leading to the formation of FTMH from the stage of the focal vitreomacular traction. |
| Databáze: | OpenAIRE |
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