Ipsilateral M1 transcranial direct current stimulation increases excitability of the contralateral M1 during an active motor task: Implications for stroke rehabilitation
| Autor: | Dawson Kidgell, Ash Frazer, Ashlee M. Hendy, Makii Muthalib, Alicia M. Goodwill, Stéphane Perrey, Wei-Peng Teo |
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| Jazyk: | angličtina |
| Předmět: |
medicine.medical_specialty
Excitability Transcranial direct-current stimulation medicine.medical_treatment Primary motor cortex Rehabilitation Stimulation Wrist Transcranial magnetic stimulation Stroke Physical medicine and rehabilitation medicine.anatomical_structure Neuroplasticity medicine Silent period Orthopedics and Sports Medicine Transcranial direct current stimulation Psychology Neurorehabilitation |
| Zdroj: | Annals of Physical and Rehabilitation Medicine. :e1-e2 |
| ISSN: | 1877-0657 |
| DOI: | 10.1016/j.rehab.2015.07.008 |
| Popis: | IntroductionAnodal transcranial direct current stimulation (a-tDCS) of the primary motor cortex (M1) elicits an increase in cortical excitability that outlasts the period of stimulation. However, little is known about effects of a-tDCS on the contralateral M1 during and after ipsilateral M1 stimulation. Therefore, we investigated the changes in corticospinal excitability and inhibition of the left M1 during and after 20min of a-tDCS to the right M1.Material and methodsEight healthy participants received real (2mA) and SHAM a-tDCS to the right M1 randomized across 2 testing sessions. Single- and paired-pulse transcranial magnetic stimulation (TMS) was applied to the left M1 to measure changes motor-evoked potential (MEP) amplitude from the right extensor carpi radialis (ECR) at 130% of resting and active motor threshold, cortical silent period (CSP) and short-interval cortical inhibition (SICI). Active motor threshold was measured during a wrist extension contraction that was less than 5% of maximal electromyographic activation of the ECR. TMS measurements were recorded at baseline, every 5min for 20min during and 10min after a-tDCS.ResultsThe results showed a significant (P |
| Databáze: | OpenAIRE |
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